1-(5-ISOQUINOLINYLSULFONYL)PIPERAZINE 2HCL

Name	1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
Synonyms	C-1 HA-100 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE 1-(5-isoquinolinylsulfonyl)piperazine 1-(5-isoquinolinylsulfonyl)-piperazin 1-(5-ISOQUINOLINYLSULFONYL)PIPERAZINE 2HCL 1-(5-ISOQUINOLINYLSULFONYL)-PIPERAZINE HYDROCHLORIDE 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
CAS	84468-24-6

Molecular Formula	C13H15N3O2S
Molar Mass	277.34
Melting Point	>240°C (dec.)
Solubility	DMSO, Methanol, Water
Appearance	Off-white lyophilized solid.
Color	Off-White to Pale Yellow
Storage Condition	Keep in dark place,Sealed in dry,2-8°C
In vitro study	HA-100 inhibits MLC-kinase and PKC competitively with respect to ATP, and the K i values are 61 and 6.5 μM, respectively.

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
RTECS	TM0862600

Last Update：2024-01-02 23:10:35

biological activity	HA-100 is an inhibitor of cGMP-dependent protein kinase (PKG),cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC kinase (MLC-kinase), with IC50 values of 4, 8, 12 and 240 μM respectively.
target	PKC 12 μ m (IC 50 ) PKG 4 μ m (IC 50 ) PKA 8 μ m (IC 50 ) MLCK 240 μ m (IC 50 ) PKC 6.5 μ m (Ki) MLCK 61 μ m (Ki)
in vitro study	HA-100 inhibits MLC-kinase and PKC competitively with respect to ATP, and the K I values are 61 and 6.5 μ M, respectively.

Last Update：2024-04-09 02:00:00

Product Name: 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Visit Supplier Webpage Request for quotation
CAS: 84468-24-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Wechat: 18301782025

View History

1-(5-ISOQUINOLINYLSULFONYL)PIPERAZINE 2HCL

1-(5-ISOQUINOLINYLSULFONYL)PIPERAZINE 2HCL Request for Quotation